1. Ntini a ɛyɛ den .
Ntini a ɛyɛ den, sɛ́ nnuru a wɔtaa de di dwuma no, wɔ nneɛma a ɛbɔ ho ban na ɛma ɛyɛ den yiye. Wɔn nneɛma atitiriw ne gelatin ne nneɛma a wɔde boa, na ɛfata sɛ wɔde nnuru a ɛyɛ den a wɔde yɛ aduru anaa granules hyɛ mu. Wɔde nnuru a ɛyɛ den di dwuma kɛse wɔ nnuruyɛ mu, titiriw wɔ akwahosan ho nneɛma, aduannuru a wɔde ma, ne nneɛma a wɔde yɛ nnuru mu. Esiane wɔn su pa a wɔde hyɛ mu nti, wobetumi asiw nnuru no ano na ayɛ oxidized, na ɛnam so ama nnuru no mu nneɛma a ɛyɛ adwuma no agyina.
Nneɛma a wɔyɛ de yɛ nneɛma a ɛyɛ den no titiriw ne anammɔn te sɛ gelatin a woyi, kɔla a wɔde yi kɔla, nea ɛma emu da hɔ, nea ɛwɔ mu, protein a woyi fi mu, ne nea ɛma ɛyɛ hyew. Wɔ nnansa yi mfe mu no, bere a mfiridwuma anya nkɔso bere nyinaa no, wɔde nneɛma foforo a ɛyɛ den a wɔde hyɛ mu te sɛ afifide a wɔde hyɛ mu ne nsu a ɛtumi sɛe no adi dwuma nkakrankakra wɔ gua so. Saa hard capsules ahorow foforo yi wɔ biocompatibility a eye, biodegradability, ne nneɛma a atwa yɛn ho ahyia adwumayɛ, na adetɔfo ani gye ho kɛse.
Hard capsule gua no, ɛwom sɛ akansi kɛse de, nanso ɛkyerɛ nkɔso ho nsɛm bi. Nea edi kan no, ahwehwɛde a ɛfa-quality ne high-purity gelatin ho no kɔ so nyin, na ɛma nnwuma a wɔyɛ nneɛma no ma wɔn mfiridwuma ho nimdeɛ ne ne su a ɛyɛ papa no yɛ kɛse. Nea ɛto so abien no, bere a adetɔfo adwene a wɔde si akwahosan ne nneɛma a atwa yɛn ho ahyia ho banbɔ so no kɔ soro no, wɔhwɛ kwan sɛ gua so kyɛfa a wonya wɔ nhabannuru a wɔde hyɛ mu ne nneɛma a wɔde hyɛ nipadua no mu a ɛtumi sɛe no mu no bɛtrɛw akɔ akyiri. Awiei koraa no, nnwinnade a wɔde yɛ nneɛma a nyansa wom ne nneɛma a wɔde yɛ nneɛma a wɔde di dwuma wɔ afiri a ɛyɛ den mu a wɔde di dwuma no reyɛ kɛse nkakrankakra, na ɛma nneɛma a wɔyɛ no yiye ne nneɛma a wɔyɛ no yɛ papa.
2. Ntini a ɛyɛ mmerɛw .
Ntini a ɛyɛ mmerɛw, sɛ́ nnuru a wɔde di dwuma wɔ ɔkwan a ɛyɛ mmerɛw so no, agye gyinabea titiriw wɔ nnuruyɛ gua so esiane mfaso soronko a ɛwɔ so nti. Wɔde nneɛma te sɛ gelatin, glycerin, ne nsu na ɛyɛ, na nnuru a ɛyɛ nsu anaa semi-no betumi ayɛ mu. Ntini a ɛyɛ mmerɛw no wɔ su pa, ɛyɛ mmerɛw sɛ wɔbɛmene, na ɛkata nnuru no dɛ ne ne hua so, na enti wɔde adi dwuma kɛse wɔ akwahosan mu nneɛma, aduannuru a wɔde ka aduan ho, ne nnuru titiriw a wɔde yɛ nnuru mu.
Nneɛma a wɔyɛ de yɛ aduru a ɛyɛ mmerɛw no yɛ nea ɛyɛ den kakra, na ɛfa anammɔn ahorow pii te sɛ gelatin a woyi fi mu, wɔtew ho, wɔyɛ no ma, na wɔde hyɛ mu. Esiane sɛ mfiridwuma anya nkɔso nti, wɔayɛ ɔkwan a wɔfa so yɛ nneɛma a ɛyɛ mmerɛw no yiye. Sɛ nhwɛso no, wɔde Plant-based gelatin di dwuma de si atetesɛm gelatin ananmu, a ɛma nneɛma a wɔde yɛ adwuma no nya biocompatibility ne nneɛma a atwa yɛn ho ahyia no yiye. Bio nso, mfiridwuma a wɔde hyɛ nneɛma a ɛyɛ mmerɛw mu ma no nso yɛ foforo bere nyinaa, te sɛ microencapsulation mfiridwuma, a ebetumi adi nnuru a woyi fi mu no so yiye.
Wɔ gua so no, soft capsule products no gu ahorow, a nea ɛka ho ne capsules a ɛyɛ mmerɛw a wɔtaa de di dwuma, a ɛkɔ so-gyae soft capsules, ne soft capsules a wɔde wɔn ani asi so. Ɛnam sɛ adetɔfoɔ di akwahosan ne wɔn ankasa ho akyi nti, soft capsule gua no kyerɛ nkɔsoɔ a ɛdidi soɔ yi: nea ɛdi kan no, ahwehwɛdeɛ a ɛfa-quality ne high-purity plant-based soft capsules ho no renya nkɔanim. Nea ɛto so abien no, mfiridwuma a ɛkɔ so-Mfiri adi ne mfiridwuma a wɔde wɔn ani asi so no abɛyɛ mmeae a ɛyɛ hyew wɔ soft capsule nhwehwɛmu ne nkɔso mu. Nea ɛto so abiɛsa no, bere a nneɛma a atwa yɛn ho ahyia ho nimdeɛ akɔ anim no, wɔhwɛ kwan sɛ nneɛma a ɛyɛ mmerɛw a ɛtumi sɛe no bɛyɛ nea wɔpɛ foforo wɔ daakye gua so. Saa nneɛma yi kyerɛ sɛ soft capsule gua no begye nkɔso beae a ɛtrɛw atom.
3. Enteric-aduru a wɔde akata so .
Enteric-aduru a wɔde akata so .yɛ aduru titiriw bi a wɔde yɛ aduru. Nea ɛho hia titiriw ne sɛ wɔmfa yafunu mu nsu ngu na mmom wogyae aduru no wɔ dwensɔtwaa mu. Wɔayɛ saa capsule nhyehyɛe yi sɛ ɛbɛbɔ aduru no ho ban na yafunu mu acid asɛe no na wɔahwɛ ahu sɛ aduru no gyae wɔ dwensɔtwaa no mu, na ɛnam so ama aduru no atumi atwe ne ho na ayɛ adwuma yiye. Enteric-aduru a wɔde akata so no ho hia titiriw wɔ yafunu a ɛnyɛ dɛ anaa nnuru a ɛyɛ mmerɛw sɛ ɛbɛsa yafunu mu acid, te sɛ nnuru a ekum ɔyare mmoawa, nnuru a ekum ɔyare mmoawa, ne nnuru bi a ɛma nipadua no yɛ adwuma no ayaresa mu.
Nneɛma a wɔyɛ wɔ enteric-aduru a wɔde akata so no yɛ ahwehwɛde kɛse. Mpɛn pii no, wɔde nneɛma titiriw a ɛkorɔn-Molecular nneɛma di dwuma sɛ capsule shells, a ɛnyɛ nea ɛpete wɔ yafunu mu acid mu nanso ebetumi apete ntɛmntɛm wɔ alkaline tebea a ɛwɔ dwensɔtwaa no mu. Wɔ adeyɛ no mu no, ɛsɛ sɛ wɔhwɛ sɛnea capsule abon no mu duru ne sɛnea ɛyɛ pɛ no so denneennen na ama wɔatumi ayi aduru no adi pɛpɛɛpɛ wɔ dwensɔtwaa no mu. Ɛnam biotechnology a wɔreyɛ so no, Enteric-Nneɛma a wɔde capsule a wɔakata so te sɛ nneɛma a ɛtumi sɛe no repue bere nyinaa, ɛma nneɛma a atwa yɛn ho ahyia no adamfofa ne nneɛma a ɛma nkwaboaa no hyia no yɛ kɛse bio.
4. Capsules ahorow afoforo .
Sɛ yɛyi hard capsules, soft capsules ne enteric-coated capsules no to nkyɛn a, capsules ahodoɔ foforɔ wɔ hɔ a ɛwɔ gua so, a emu biara wɔ ne dwumadie tebea soronko ne mfasoɔ. Sɛ nhwɛso no, kɔ so-aduru a wɔde gyae no betumi ahwɛ sɛnea nnuru no gyae no so, na ɛma mogya mu nnuru dodow a ɛyɛ den wɔ nipadua no mu, a ɛfata ma nyarewa a enni sabea a egye bere tenten-bere a wɔde sa yare no. Nsiesiei a ɛkɔ so-release capsules no betumi atew mpɛn dodow a nnuru ma ayarefo no so na ama wɔn mmara sodi atu mpɔn.
Capsules a wɔde wɔn ani asi so no yɛ capsule bi a ebetumi de nnuru akɔ mmeae pɔtee bi tẽẽ. Ɛdenam mfiridwuma pɔtee bi a wɔde wɔn ani si so te sɛ antibody conjugation anaa magnetic targeting so no, nnuru betumi akwati ntini a ɛnyɛ{1}}aduru a wɔde si wɔn ani so no na wɔatew nea efi mu ba no so. Saa capsule yi ho hia titiriw wɔ kokoram ayaresa mu efisɛ ebetumi ama ayaresa tumi no ayɛ kɛse bere a ɛtew ɔsɛe a ɛba ntini a ɛteɛ so no so. Nhwehwɛmu ne nea wɔde di dwuma wɔ capsules a wɔde wɔn ani asi so no gyina hɔ ma nkɔso kɛse wɔ nnuru a wɔde ma ho mfiridwuma mu.
Sɛ́ aduru foforo a wɔde hyɛ mu no, wɔde nkakrankakra retwe adwene afi gua no so. Wɔtaa de afifide mu protein ahorow te sɛ gelatin si ananmu, na ɛma wonya biocompatibility a eye na ɛyɛ mmerɛw sɛ ɛbɛsɛe. Ɛnyɛ sɛ saa capsules yi di nneɛma a atwa yɛn ho ahyia ho banbɔ ho ahwehwɛde ahorow so nko na mmom ɛma wonya akwan pii ma wɔn a wonni nam ne wɔn a wɔn ho nyɛ wɔn den wɔ mmoa ho-anya gelatin. Esiane sɛ nnipa a wɔde di dwuma no nya akwahosan ne nneɛma a atwa yɛn ho ahyia ho banbɔ ho nimdeɛ kɛse nti, gua so tumi a ɛwɔ nhabannuru a wɔde hyɛ mu no yɛ kɛse.
